Tetralysal 408mg Capsules & Differin Cream/Gel

Tetralysal 408mg Caps & Differin 0.1% Cream/Gel Combined Therapy

This combination offers a comprehensive approach to acne treatment. Tetralysal is an oral antibiotic that works systemically to reduce acne-causing bacteria, while Differin 0.1% Cream/Gel contains Adapalene, a retinoid that promotes skin cell turnover, unclogs pores, and reduces inflammation. Together, these medications provide an effective solution for managing acne. Consistent use for a minimum of 3 months is recommended for optimal results, although some individuals may notice improvements sooner.

Understanding Acne

Acne is a common skin condition that causes spots, oily skin, and sometimes, painful or warm sensations when touching the affected areas. While acne is common in teenagers, it can occur at any age.

Essential Facts on Acne:

• Types of Spots: Acne can appear in various forms, including:
  • Blackheads: Small, dark spots on the surface of the skin.
  • Whiteheads: Firm spots that are difficult to extract.
  • Papules: Small, red, tender bumps.
  • Pustules: Red spots with pus-filled heads.
  • Nodules: Large, painful lumps located deep beneath the skin.
  • Cysts: Large, pus-filled lumps that can result in scarring.
• Causes: The exact cause of acne is not fully understood, but factors such as hormonal changes, certain medications, and diet can contribute to its development. Hormonal fluctuations may lead to excess oil production, which, when combined with dead skin cells, can block pores and cause acne outbreaks.
• Who Gets Acne: Acne is most common among teenagers and young adults due to hormonal changes during puberty, but many adults, especially women, can also experience acne.
• Identifying Acne: Regular breakouts, particularly in the 'T-zone' (forehead, nose, chin), or oily skin with different types of spots may indicate acne.

Choosing the Right Acne Treatment:

Understanding the type and severity of your acne is key to selecting the right treatment. Over-the-counter (OTC) treatments may work for mild cases, but more severe forms often require prescription medications. If you're unsure about your acne type or if OTC treatments aren't working, consider completing our Express Consultation Form. Our specialists can guide you toward the most suitable treatment for your condition.

The combination of Tetralysal 408mg Caps and Differin 0.1% Cream/Gel offers a powerful dual approach to acne treatment:

Tetralysal 408mg Caps:

Tetralysal is an antibiotic that is highly effective against bacteria contributing to acne development, particularly Cutibacterium acnes. It works by inhibiting bacterial protein synthesis, preventing their growth and spread. This results in a significant reduction in acne-causing bacteria, leading to fewer inflamed and non-inflamed lesions on the skin.

Differin 0.1% Cream/Gel:

Differin contains Adapalene, a topical retinoid specifically formulated to target acne. It promotes faster skin cell turnover, unclogs pores, and reduces the formation of blackheads and whiteheads. Additionally, Adapalene helps reduce inflammation and smooth the skin's texture. Together, Differin and Tetralysal provide a comprehensive treatment for managing both active acne and preventing future breakouts.

Always read the provided patient information leaflet before taking or applying any medication, and follow the instructions provided by your healthcare professional. Here's a basic guideline for using this combination treatment:

Set-up:

• Start with clean hands. Wash them thoroughly with soap and water.
• Cleanse the area affected by acne with a mild, non-medicated cleanser. Ensure the cleanser is free from alcohol or other potential skin irritants.
• Pat your skin dry with a soft towel. Avoid rubbing vigorously.

Procedure for Tetralysal 408mg Capsules:

• Take the Tetralysal capsule with a full glass of water.
• Avoid lying down for at least 10 minutes after taking the capsule to prevent throat irritation.
• Always follow your doctor's advice regarding the dosage and timing.

Procedure for Differin 0.1% Cream/Gel:

• After ensuring the skin is clean and dry, apply a small amount of Differin Cream or Gel to the affected areas.
• Gently massage the product into the skin in circular motions until fully absorbed, avoiding the eyes, nose, and mouth.

Aftercare:

• Avoid washing the treated skin immediately after application. Ideally, keep the medication on the skin for several hours or as recommended by your healthcare provider.
• If you experience skin dryness or irritation, consider using a non-comedogenic moisturizer suitable for acne-prone skin.
• If heading outdoors, protect your skin with a broad-spectrum sunscreen with an SPF of 30 or higher, as acne treatments can increase sun sensitivity.

Usage Frequency:

Differin is usually applied once daily, typically in the evening, while Tetralysal’s dosage will be as prescribed by your doctor. Make sure to follow the recommended guidelines for both.

Guiding Notes:

• When starting new acne treatments, introduce them slowly to monitor any skin reactions.
• If unusual symptoms such as increased irritation or redness appear, stop use and consult your healthcare professional.
• Avoid using other medicinal skin products unless approved by your doctor.
• Patience is important. Results from acne treatments can take several weeks. Be sure to follow your healthcare expert's advice and check in regularly regarding your progress or any concerns.

Skin Sensitivity:

Using Tetralysal and Differin may occasionally lead to skin dryness, peeling, or irritation, especially in the early stages of treatment. If these symptoms persist or worsen, stop using the products and consult your healthcare professional.

Sun Exposure:

Tetralysal may increase your skin's sensitivity to sunlight. Limit direct sun exposure while taking this medication, and always use sunscreen with at least SPF 30 when outdoors. Avoid tanning booths and sunlamps.

Allergic Reactions:

Although uncommon, allergic reactions can occur. If you experience severe redness, swelling, itching, or rashes, discontinue use immediately and seek medical attention.

Eyes, Nose, and Mouth:

Avoid contact of Differin cream/gel with your eyes, nostrils, mouth, or other sensitive areas. If accidental contact occurs, rinse thoroughly with water.

Concurrent Use of Other Products:

Do not use other medicinal skin products simultaneously, especially those containing peeling agents (such as salicylic acid), unless directed by a healthcare professional.

Open Wounds:

Avoid applying Differin to sunburned, chapped, or broken skin.

Oral Medication Interactions:

If you are taking other oral medications, especially other acne treatments, talk to your doctor or pharmacist before starting Tetralysal or Differin to prevent possible interactions.

Alcohol-based Products:

Avoid using alcohol-based skincare products while using Differin, as they may increase skin dryness and irritation.

Storage:

Store both products at room temperature, away from direct sunlight, and keep them out of reach of children.

Points to Remember:

• Always read the patient information leaflet that comes with each product, and consult your healthcare provider if you have any concerns or notice unusual symptoms.
• Tetralysal is associated with potential risks such as antibiotic-related diarrhea or colitis. If you experience these symptoms, stop taking the medication and contact your doctor immediately.
• Keep both products out of children's reach.
• While Differin is for external use, Tetralysal is taken orally. Follow the instructions for each product carefully, and take extra care when using Differin around sensitive areas like the eyes.
• If you suspect an allergic reaction to any of the ingredients, stop using the products. For any side effects such as rashes or irritation, discontinue use and consult a healthcare professional.

Do not use Tetralysal or Differin during pregnancy or while breastfeeding due to potential risks. There are alternatives that are safer and more effective for these particular scenarios. For detailed advice on managing acne during pregnancy, please see our Acne guide.

Ingredients: Tetralysal 408mg Capsules and Differin 0.1% Cream/Gel Combination Treatment

Tetralysal 408mg Capsules:

Active Ingredient:

Lymecycline (equivalent to 408mg Tetralysal).

Inactive Ingredients:

Magnesium Stearate, Gelatin, Titanium Dioxide (E171), Indigo Carmine (E132), Yellow Iron Oxide (E172).

Differin 0.1% Cream:

Active Ingredient:

Adapalene (0.1%).

Inactive Ingredients (Cream):

Carbomer, Cyclomethicone, Glycerol, Methyl Parahydroxybenzoate (E218), Phenoxyethanol, Sodium Hydroxide, Edetate Disodium, Squalane, Purified Water.

Differin 0.1% Gel:

Active Ingredient:

Adapalene (0.1%).

Inactive Ingredients (Gel):

Carbomer, Propylene Glycol, Poloxamer 182, Disodium Edetate, Methyl Parahydroxybenzoate (E218), Phenoxyethanol, Sodium Hydroxide, Purified Water.

Note:

It is advisable to perform a patch test before introducing a new product into your routine to check for potential allergic reactions or sensitivities. If any irritation or adverse reactions occur, discontinue use immediately and consult a healthcare professional for advice.

Potential Side Effects

All treatments have the potential for side effects. If you experience severe side effects, or if mild side effects persist, it's important to seek advice from your pharmacist or doctor without delay. This summary may not cover all possible side effects, so it's always recommended to consult the patient information leaflet for a comprehensive list.

When using Tetralysal 408mg caps in combination with Differin 0.1% Cream/Gel, side effects may result from either medication or both. Not everyone will experience these side effects, and in many cases, they are temporary and will subside on their own. Below are the potential side effects for each medication:

Tetralysal 408mg Caps:

Common Side Effects (may affect up to 1 in 10 people):

• Nausea
• Headache
• Sensitivity to sunlight
• Upset stomach

Uncommon Side Effects (may affect up to 1 in 100 people):

• Vomiting
• Rash
• Dizziness

Rare Side Effects (may affect up to 1 in 1,000 people):

• Yeast infections
• Increased pressure in the skull

Differin 0.1% Cream/Gel:

Common Side Effects (may affect more than 1 in 10 people):

• Dryness or peeling of the skin
• Redness at the application site
• Burning or stinging sensation

Uncommon Side Effects (may affect up to 1 in 100 people):

• Itching
• Skin irritation
• Increased sensitivity to sunlight

Rare Side Effects (may affect up to 1 in 1,000 people):

• Severe skin reactions or blistering
• Skin discoloration
• Allergic contact dermatitis

If any side effects become severe or if they persist and cause discomfort, consider discontinuing the product and promptly seek medical advice.

Choosing the Right Acne Treatment

If you need a diagnosis, you can use our Express Consultation Form

Understanding that the cause and severity of acne varies among individuals is essential. Hence, the optimal treatment might differ for each person. Below is a list of alternative treatments:

Over-the-Counter (OTC) Options:

• Salicylic Acid Products: Useful for unclogging pores. Available as cleansers, toners, and spot treatments.
• Benzoyl Peroxide: A popular ingredient in many OTC acne products. It helps reduce acne-causing bacteria and can mitigate inflammation.
• Alpha Hydroxy Acids: Effective in removing dead skin cells and unclogging pores.
• Cetaphil Gentle Skin Cleanser: A formula that's friendly to all skin types, helping eliminate excess oil without causing dryness.
• Cetaphil Moisturising Lotion: Offers hydration suitable for all skin types.
• Aveeno Cream and Lotion: Enriched with colloidal oatmeal, renowned for its calming properties.

Prescription Products:

• Differin 0.1% Gel and Cream: Contains adapalene, a kind of retinoid, known for its pore-unclogging and anti-inflammatory properties.
• Duac Gel (3% & 5%): Features benzoyl peroxide and clindamycin, an antibiotic effective in curbing bacteria growth.
• Skinoren 20% Cream: Packed with azelaic acid, which showcases anti-inflammatory and comedolytic properties.
• Oral Antibiotics: Examples include Doxycycline, Oxytetracycline, and Minocycline. They work by reducing bacteria and inflammation.
• Oral Contraceptives: Like Dianette and Eloine, they can manage hormones that trigger acne in females.
• Spironolactone: Originally designed for high blood pressure treatment, but it can also address acne in women by counteracting the effects of androgens on the skin.

Combination Treatments:

• Dalacin-T Lotion / Acnecide 5% gel Combination Treatment
• Zindaclin 1% gel / Differin 0.1% cream/gel Combination Treatment
• Doxycycline 100mg caps /Differin 0.1% cream/gel Combination Treatment