Zindaclin Gel & Differin Cream/Gel

Zindaclin 1% Gel and Differin 0.1% Gel/Cream are prescription-only formulations created to address the challenges of mild to moderate acne. Zindaclin contains the active ingredient Clindamycin, an antibiotic known to fight acne-causing bacteria. On the other hand, Differin 0.1% Gel/Cream features Adapalene, a type of retinoid, which helps reduce inflammation and promotes faster skin cell turnover. When used in conjunction, these products offer a comprehensive approach to acne management, targeting both the causes and visible symptoms of acne.

Should I pick Differin Gel or Differin Cream?

The choice between Differin Gel and Cream depends on your skin type and personal preference. The gel formulation is typically lighter and might be more suitable for individuals with oily skin, as it can be absorbed faster and may leave a less greasy residue. The cream, however, may be more fitting for those with dry or sensitive skin, offering a moisturising effect. It's always best to consult with a healthcare professional or dermatologist to determine the most appropriate option for your specific needs.

Zindaclin 1% Gel: Clindamycin, the active ingredient in Zindaclin, is an antibiotic that combats the bacteria present in acne. It specifically targets Propionibacterium acnes, a primary contributor to acne development. Clindamycin hampers bacterial protein synthesis, diminishing the number of acne-causing bacteria, resulting in reduced inflammation and fewer breakouts.

Differin 0.1% Gel/Cream: Differin's primary component, Adapalene, is a type of retinoid. Derived powerfully from Vitamin A, retinoids influence skin cell growth and mitigate inflammation. This action helps to unclog pores, decrease redness, and forestall future breakouts. Additionally, it facilitates skin surface renewal, promoting even skin texture and minimizing post-acne marks.

Employing these two products in tandem delivers a comprehensive strategy to combat acne, addressing both the underlying causes and external symptoms.

Zindaclin 1% Gel:

• Begin by cleansing your face, then pat dry.
• Administer a thin layer to the affected areas once daily, ideally during the evening or as advised by your dermatologist.
• Steer clear of the eyes, mouth, and open wounds to prevent irritation.

Differin 0.1% Gel/Cream:

• Ensure your face is cleansed and dry prior to application.
• Gently spread a thin layer of the gel/cream across the entire face and other affected regions.
• It's recommended to use the product once daily, preferably in the evening.
• Avoid areas near the eyes, mouth, or open wounds to prevent irritation.

Note: Both products can heighten sensitivity to sunlight. Always apply sunscreen during the day and minimize sun exposure while using these treatments. In case of irritation, consider reducing the frequency of application or discontinuing the product temporarily and seek advice from a healthcare professional.

Zindaclin 1% Gel – Precautions:

• Be cautious to avoid contact with eyes, mouth, and mucous membranes. In case of accidental contact, ensure to rinse thoroughly with water.
• Do not apply on open wounds or any broken skin areas.
• If you observe signs of irritation or excessive skin dryness, consider reducing the application frequency or even discontinuing the product temporarily.
• Note that this product might increase sensitivity to sunlight. Always wear sunscreen and try to limit direct sun exposure when using it.

Differin 0.1% Gel/Cream – Precautions:

• This is strictly for external application only.
• Avoid touching the eyes, lips, and mucous membranes with this product. Rinse off immediately with water if such contact occurs.
• Immediate cessation is advised if you experience intense redness, swelling, or irritation. Consult a healthcare professional for guidance.
• Minimize sun exposure during the duration of this treatment. Sunscreen application during daytime is a must.

Important: For comprehensive guidance, it's recommended to thoroughly read the patient information leaflets of both products. Should you have doubts or concerns about any precautionary note, it's best to consult a healthcare expert before product usage.

• Zindaclin 1% gel and Differin 0.1% gel/cream should not be used during pregnancy, when planning a pregnancy, or while breastfeeding, as it can potentially harm an unborn child. It's safe for use only by women who are taking effective contraceptive measures. Should you become pregnant while on this medication, stop the treatment immediately and consult with your G.P.

Understanding the ingredients in your medications is crucial. It helps avoid potential allergens and provides insight into the product's composition. Below are the ingredients for Zindaclin 1% gel and Differin 0.1% gel/cream:

Zindaclin 1% Gel:

• Active ingredient: Clindamycin (as phosphate) 1%
• Other ingredients: Propylene glycol, ethanol, zinc acetate, hydroxyethyl cellulose, sodium hydroxide, water.

Differin 0.1% Gel/Cream:

• Active ingredient: Adapalene 0.1%
• Other ingredients for gel: Carbomer 940, propylene glycol, poloxamer 182, sodium hydroxide, purified water.
• Cream formulation: Refer to the product leaflet for additional ingredients specific to the cream.

In case of suspected allergies or sensitivities to any listed ingredient, discontinue the product and seek medical advice immediately.

Every medication has the potential to cause side effects. While many are temporary and will subside on their own, it's crucial to be informed and vigilant. If you experience severe side effects or if mild side effects persist, it is essential to consult your pharmacist or doctor promptly. This list is not exhaustive; always refer to the patient information leaflet for a comprehensive overview. Below are potential side effects when using Zindaclin 1% gel and Differin 0.1% gel/cream:

Zindaclin 1% Gel:

• Common Side Effects (affecting up to 1 in 10 people):
  • Dry skin
  • Skin burning sensation
  • Itching of the skin
  • Redness of the skin
• Uncommon Side Effects (affecting up to 1 in 100 people):
  • Rash
  • Skin pain or irritation
  • Sunburn
• Rare Side Effects (affecting up to 1 in 1,000 people):
  • Acne
  • Skin inflammation

Differin 0.1% Gel/Cream:

• Common Side Effects (affecting more than 1 in 10 people):
  • Dry skin
  • Redness of the skin
  • Peeling of the skin
• Uncommon Side Effects (affecting up to 1 in 100 people):
  • Burning sensation
  • Itching of the skin
  • Sensitivity to sunlight
• Rare Side Effects (affecting up to 1 in 1,000 people):
  • Swelling of the face
  • Rash

If you encounter any severe or prolonged side effects, it is advised to stop using the product and seek medical attention immediately.

Choosing the Right Acne Treatment

If you need a diagnosis, you can use our Express Consultation Form

Understanding that the cause and severity of acne varies among individuals is essential. Hence, the optimal treatment might differ for each person. Below is a list of alternative treatments:

Over-the-Counter (OTC) Options:

• Salicylic Acid Products: Useful for unclogging pores. Available as cleansers, toners, and spot treatments.
• Benzoyl Peroxide: A popular ingredient in many OTC acne products. It helps reduce acne-causing bacteria and can mitigate inflammation.
• Alpha Hydroxy Acids: Effective in removing dead skin cells and unclogging pores.
• Cetaphil Gentle Skin Cleanser: A formula that's friendly to all skin types, helping eliminate excess oil without causing dryness.
• Cetaphil Moisturising Lotion: Offers hydration suitable for all skin types.
• Aveeno Cream and Lotion: Enriched with colloidal oatmeal, renowned for its calming properties.

Prescription Products:

• Differin 0.1% Gel and Cream: Contains adapalene, a kind of retinoid, known for its pore-unclogging and anti-inflammatory properties.
• Duac Gel (3% & 5%): Features benzoyl peroxide and clindamycin, an antibiotic effective in curbing bacteria growth.
• Skinoren 20% Cream: Packed with azelaic acid, which showcases anti-inflammatory and comedolytic properties.
• Oral Antibiotics: Examples include Doxycycline, Oxytetracycline, and Minocycline. They work by reducing bacteria and inflammation.
• Oral Contraceptives: Like Dianette and Eloine, they can manage hormones that trigger acne in females.
• Spironolactone: Originally designed for high blood pressure treatment, but it can also address acne in women by counteracting the effects of androgens on the skin.

Combination Treatments:

• Dalacin-T Lotion / Acnecide 5% gel Combination Treatment
• Zindaclin 1% gel / Differin 0.1% cream/gel Combination Treatment
• Doxycycline 100mg caps /Differin 0.1% cream/gel Combination Treatment