Zindaclin 1% Gel and Acnecide 5% Gel

Zindaclin 1% gel & Acnecide 5% gel Combined Therapy

This therapeutic duo has been meticulously designed for effective acne management. The antibacterial attributes of Zindaclin directly target and diminish acne-causing bacteria. Meanwhile, Acnecide's benzoyl peroxide component assists in exfoliating the skin and mitigating inflammation. When applied together, these products synergize to furnish a holistic remedy for acne. For best results, a consistent application is suggested over a span of at least 3 months, although many users report seeing improvements within a few weeks.

Understanding Acne

Acne, a common skin ailment, manifests as spots, an oily skin texture, and occasionally, skin that feels hot or sore to touch. While predominantly affecting teenagers, it isn't exclusive to any age group.

Essential Facts on Acne:

• Spot Varieties: Acne presents itself in multiple forms:
  • Blackheads: Small darkened patches on the skin.
  • Whiteheads: Tight spots that are challenging to express.
  • Papules: Small, inflamed, red raised spots.
  • Pustules: Red spots topped with pus.
  • Nodules: Painful, larger lumps beneath the skin's surface.
  • Cysts: Boil-like, pus-filled lumps that can result in scarring.
• Underlying Factors: Though the precise cause remains elusive, factors like hormonal changes, specific medications, and diet play a role. A surge in hormones can stimulate the sebaceous glands to produce excess oil. When this oil amalgamates with dead skin cells, it can obstruct pores, giving rise to acne.
• Demographics: Acne primarily afflicts teenagers and young adults due to hormonal changes during puberty. Nonetheless, a significant number of adults, particularly women, grapple with acne later in life.
• Determining Acne: If you notice frequent breakouts, especially in the 'T-zone' region (forehead, nose, chin), or if your skin feels oily and has varied types of spots, you might be dealing with acne.

Selecting an Acne Remedy:

Recognizing the type and intensity of your acne is paramount. While over-the-counter remedies can suffice for mild cases, more severe instances might necessitate prescription treatments. If you're uncertain about your acne type or find common treatments ineffective, consider completing our Express Consultation Form, and our team will guide you to the most appropriate treatment for your condition.

The duo of Zindaclin 1% gel and Acnecide 5% gel presents a dual strategy for tackling acne:

Zindaclin 1% gel (Clindamycin):

Zindaclin's main component, Clindamycin, is an antibiotic that zeroes in on bacteria pivotal in acne's formation, chiefly Propionibacterium acnes. It disrupts the protein synthesis of these bacteria, curtailing their growth and multiplication. Consequently, there's a marked reduction in the presence of bacteria that trigger acne, leading to a decrease in both inflamed and non-inflamed blemishes.

Acnecide 5% gel (Benzoyl Peroxide):

Benzoyl peroxide is multifunctional in its action against acne. Primarily, it boasts antimicrobial qualities that diminish the quantity of acne-inducing bacteria on the skin. It also facilitates keratolysis, promoting the shedding of the skin's external layer. This aids in decongesting pores, which in turn minimizes the emergence of blackheads and whiteheads. Additionally, its anti-inflammatory attributes help in alleviating redness and puffiness associated with acne lesions.

Always peruse the included patient information guide before applying any medication and adhere to the directives given by your medical expert. Below is a foundational procedure for employing this combination therapy:

Set-up:

• Initiate with hygienic hands. Ensure they're cleansed with soap and water.
• Wash the acne-prone region with a mild, non-medicated cleanser. If you opt for a cleaning agent, verify that it's devoid of alcohol or other potential skin irritants.
• Using a gentle towel, dab your skin until dry. Refrain from vigorous rubbing.

Procedure for Zindaclin 1% gel:

• Dispense a small bead-sized quantity of the gel on your fingertip.
• With care, spread a sheer layer of the gel over the problematic zones.
• Wait for a short while allowing the gel to air-dry before proceeding.

Procedure for Acnecide 5% gel:

• Following the drying of the Zindaclin gel, allocate a modest amount of Acnecide gel to your fingertip.
• Smoothly administer a slender layer on the problem areas, taking care to sidestep the eyes, nose, and lips.
• Exercise caution with benzoyl peroxide products; they have a known propensity to bleach hairs and dyed textiles.

Aftercare:

• Refrain from rinsing the treated skin immediately post-application. Ideally, retain the medication on the skin for multiple hours or as suggested by your medical advisor.
• If sensations of skin parchedness or irritation surface, think about employing a non-comedogenic hydrating lotion fit for skin prone to acne.
• If planning an outdoor jaunt, shield your skin with a comprehensive sunscreen boasting an SPF of 30 or above, since acne remedies can heighten sun sensitivity.

Usage Regularity:

Commonly, these gels are meant for once-a-day application, preferably during nighttime, or as stipulated by your medical practitioner. Should you perceive heightened skin sensitivity with concurrent usage, contemplate alternating the gels: one for the morning and the other for the night.

Guiding Notes:

• When introducing new acne solutions, it's pivotal to do so progressively to gauge any skin responses.
• If any anomalies like heightened irritation or redness manifest, halt usage and seek guidance from your health professional.
• Steer clear of using other therapeutic skin products unless greenlit by your physician.
• Persistence is paramount. Achieving visible results with acne solutions can be a waiting game, spanning several weeks. It's vital to stay aligned with your healthcare expert's guidance and routinely touch base regarding your improvement and any apprehensions.

Skin Sensitivity:

Usage of these products may occasionally lead to symptoms like skin dryness, peeling, or irritation, especially during initial phases of the regimen. Should these symptoms persist or intensify, cease usage and confer with your medical professional.

Sun Exposure:

Acne formulations may heighten skin sensitivity to sun rays. Minimize exposure to the sun when utilizing these products, and always ensure you apply a sunscreen boasting a minimum of SPF 30 during outdoor activities. Tanning booths and sunlamps should be avoided.

Bleaching:

Note that Acnecide comprises benzoyl peroxide, a component known to bleach hair and fabrics. Exercise caution during application. Opting for older attire and white bedding during the treatment phase might be prudent.

Allergic Reactions:

While uncommon, allergic episodes can arise. Should you notice symptoms such as pronounced redness, swelling, itching, or skin eruptions, cease usage and promptly seek medical consultation.

Eyes, Nose, and Mouth:

Exercise caution to prevent the product from coming into contact with the eyes, nostrils, mouth, or other sensitive regions. In the event of accidental contact, promptly rinse with copious amounts of water.

Concurrent Use of Other Products:

Avoid the simultaneous use of other medicinal skin products, especially those with peeling agents (e.g., salicylic acid or tretinoin) unless otherwise advised by a medical expert.

Pregnancy and Breastfeeding:

If you are pregnant, considering pregnancy, or are in the breastfeeding phase, it's imperative to discuss with your physician prior to using these products. When breastfeeding, steer clear of product application in the vicinity of the chest.

Open Wounds:

Abstain from applying on compromised, sun-afflicted, or inflamed skin, as well as open lesions.

Oral Medication Interactions:

Should you be on oral medications, notably other acne formulations, it's recommended to confer with your physician or pharmacist before starting these products to preclude potential adverse interactions.

Alcohol-based Products:

Desist from utilizing alcohol-infused products on the skin in tandem with this combined regimen, as this may exacerbate skin dryness and irritation.

Storage:

Products should be stored under room temperature conditions, shielded from direct sunlight, and kept inaccessible to children.

Points to Remember:

• Always peruse the patient information brochure accompanying each product and liaise with your healthcare expert should you harbor concerns or discern abnormal symptoms.
• Though exceedingly rare, conditions like antibiotic-associated diarrhoea and colitis have been linked to this medication. Should you encounter these ailments, immediately cease medication intake and promptly seek medical counsel.
• Ensure the product remains concealed from children's sight and reach.
• This product is strictly for external application – ingestion is strongly discouraged, and caution should be exercised around the eyes.
• If you discern or suspect allergic reactions to any of the constituents, desist from using. For any suspected adverse effects, like rashes or irritations, discontinue usage and consult a medical professional.

We would not advise the use of this medication during pregnancy or breastfeeding due to potential risks. There are likely safer and more effective alternative treatments available for these specific situations. For comprehensive guidance on managing acne during pregnancy, please refer to our Acne guide.

Ingredients: Zindaclin 1% gel and Acnecide 5% gel Combination Treatment

Zindaclin 1% Gel:

Active Ingredient:

Clindamycin phosphate (equivalent to 1% clindamycin).

Inactive Ingredients:

Propylene glycol, purified water, ethanol, and a base containing zinc acetate dihydrate and hydroxyethyl cellulose.

Acnecide 5% Gel:

Active Ingredient:

Benzoyl peroxide (5%).

Inactive Ingredients:

Docusate sodium, disodium edetate, poloxamer 182, carbomer 940, propylene glycol, acrylates copolymer, glycerol, colloidal anhydrous silica, sodium hydroxide, and purified water.

Note:

It's always advisable to conduct a patch test when introducing a new product to your skincare regimen to identify potential allergic reactions or sensitivities. If you encounter any irritation or negative response, cease use and seek advice from a healthcare professional.

Potential Side Effects

All medications and products can potentially lead to side effects. If they are severe, or if they're mild and don't improve, it's essential to consult with your pharmacist or doctor immediately. Note that this list might not cover all possible side effects, so always refer to the patient information leaflet for a comprehensive list.

Combining the use of Zindaclin 1% gel and Acnecide 5% gel might result in side effects stemming from either or both medications. It's worth noting that not everyone will experience these side effects, and in many instances, they are transient and resolve on their own. Here are the potential side effects for each medication:

Zindaclin 1% Gel:

Common Side Effects (may affect up to 1 in 10 people):

• Dry skin
• Sensation of skin burning
• Skin itching
• Skin redness

Uncommon Side Effects (may affect up to 1 in 100 people):

• Rash
• Discomfort or pain on the skin
• Sunburn

Rare Side Effects (may affect up to 1 in 1,000 people):

• Acne worsening
• Inflammation of the skin

Acnecide 5% Gel:

Common Side Effects (may affect more than 1 in 10 people):

• Dry skin
• Skin redness
• Sensations of burning, stinging, or tingling
• Skin peeling

Uncommon Side Effects (may affect up to 1 in 100 people):

• Skin itching
• Discomfort or pain on the skin

Rare Side Effects (may affect up to 1 in 1,000 people):

• Facial swelling, including lips, mouth, tongue, or throat which may lead to difficulties swallowing or breathing (angioedema)
• Rashes
• Increased skin sensitivity to sunlight

If you notice any severe side effects or if side effects persist or cause discomfort, it's recommended to halt use and consult a healthcare professional.

Choosing the Right Acne Treatment

If you need assistance in making a choice, you can use our Express Consultation Form. Alternatively, you can book a friendly telephone or video consultation with one of our specialized dermatology pharmacists.

Understanding that the cause and severity of acne varies among individuals is essential. Hence, the optimal treatment might differ for each person. Below is a curated list of alternative treatments categorized by availability and type:

Over-the-Counter (OTC) Options:

• Salicylic Acid Products: Useful for unclogging pores. Available as cleansers, toners, and spot treatments.
• Benzoyl Peroxide: A popular ingredient in many OTC acne products. It helps reduce acne-causing bacteria and can mitigate inflammation.
• Alpha Hydroxy Acids: Effective in removing dead skin cells and unclogging pores.
• Cetaphil Gentle Skin Cleanser: A formula that's friendly to all skin types, helping eliminate excess oil without causing dryness.
• Cetaphil Moisturising Lotion: Offers hydration suitable for all skin types.
• Aveeno Cream and Lotion: Enriched with colloidal oatmeal, renowned for its calming properties.

Prescription Products:

• Differin 0.1% Gel and Cream: Contains adapalene, a kind of retinoid, known for its pore-unclogging and anti-inflammatory properties.
• Duac Gel (3% & 5%): Features benzoyl peroxide and clindamycin, an antibiotic effective in curbing bacteria growth.
• Skinoren 20% Cream: Packed with azelaic acid, which showcases anti-inflammatory and comedolytic properties.
• Oral Antibiotics: Examples include Doxycycline, Oxytetracycline, and Minocycline. They work by reducing bacteria and inflammation.
• Oral Contraceptives: Like Dianette and Eloine, they can manage hormones that trigger acne in females.
• Spironolactone: Originally designed for high blood pressure treatment, but it can also address acne in women by counteracting the effects of androgens on the skin.

Combination Treatments:

• Dalacin-T Lotion / Acnecide 5% gel Combination Treatment
• Zindaclin 1% gel / Differin 0.1% cream/gel Combination Treatment
• Doxycycline 100mg caps /Differin 0.1% cream/gel Combination Treatment